My career as a Computer Technician Essay

In today’s time, some of the best career choices can be found within technology. A significant part of technology, computers, is an ever changing field, constantly growing and expanding to make newer, faster, better computers. One of the best fields within this division is Computer Technician. There are many reasons why this position is a position that is strived for, and a high demand job position within the workforce. I will explain the three top reasons why anyone would want to be a Computer Technician, and why it’s the best job choice for you. As you begin to look into the career choice of becoming a Computer Technician, you find out that it is a field in which you repair computers, whether it be hardware or software related. Also, you find out there are requirements needed to become one. First, you have to undergo education. â€Å"You can begin preparing to become a computer technician while still in high school. Many high schools offer certification training courses or credit towards a 2-year college degree or an associate’s degree. High school graduates can choose to pursue either a 2 or 4 year college program. Many community colleges offer computer technician training programs that focus directly on the actual jobs you will be doing out in the real world. The most important training courses you will need to take are those courses that prepare you for your certification exams! These courses can be taken as part of a degree program or on a stand-alone basis.† (n.d.3.) Coming from education, if you receive the right amount of it, the rewards can be great. â€Å"According to the BLS, the median wage of computer repair technicians is $36,000 as of 2011. The highest wages are found in technical and trade schools, at a mean wage of $67,000. Earnings are highest in states on the East Coast, specifically in the northeastern states where the mean wage can reach $41,000-$47,000.† (n.d.2.) This is a very rewarding job, considering the education requirements and the actual pay wage, this is a great start into the field and a great way to get paid! The salary, benefits, and 401k plan that are usually offered are available in this career, as well, depending on which company or place of business you work for. Coming from benefits and rewards of becoming a Computer Technician, it is also a very flexible field. Hours can be full or part time, pay can be salary or hourly. Considering there is an increase within the job market for Computer Technicians, the flexibility of having more choice in hours and pay is a significant pro to this career choice, as other jobs in other industries do not always allow such flexibility. This career choice is truly an easy one to adapt to. The requirements of becoming a Computer Technician might be a bit steep, and somewhat tedious to sit through and complete, but the benefits of becoming one are too high to ignore. The ability to stay on the cutting edge of technology, alone, is worth it, but the financial aspect of this career choice is also not one to dismiss as not worth it. Computer Technicians overall are a very admirable field to choose as a career choice, because it truly is a field in which doesn’t require years upon years of education, and the benefits are well worth reaping. REFERENCES QuinStreet Inc. (n.d.1). Retrieved from http://www.computertrainingschools.com/career-training/computer-repair-technician/ (n.d.2). Retrieved from http://diplomaguide.com/articles/Computer_Repair_Tech_Career_Overview.html (n.d.3). Retrieved from http://www.citytowninfo.com/education-articles/career-guides/how-to-become-a-computer-technician

Determinants Of Health Essay

Social determinants of health are the circumstances in which people are born, grow up, live, work, and age, as well as the systems put in place to deal with illness. These circumstances are in turn shaped by a wider set of forces: economics, social policies, and politics.Social determinants of health are factors in the social environment that contribute to or detract from the health of individuals and communities. These factors include, but are not limited to the following: Socioeconomic status,Transportation,Housing,Access to services,Discrimination by social grouping (e.g., race, gender, or class),Social or environmental stressors.Certain factors that contribute to the development of illness are: Poverty,Unemployment,High School Education, Health Insurance. Communicable diseases spread from one person to another or from an animal to a person. The spread often happens via airborne viruses or bacteria, but also through blood or other bodily fluid. The terms infectious and contagious are also used to describe a communicable disease. A communicable disease chain is the chain of infection,which includes: INFECTIOUS DISEASE:Any microorganism that can cause a disease such as a bacterium, virus, parasite, or fungus. RESERVOIR: The place where the microorganism resides, thrives, and reproduces, i.e., food, water, toilet seat, elevator buttons, human feces, respiratory secretions. PORTAL OF EXIT : The place where the organism leaves the reservoir, such as the respiratory tract (nose, mouth), intestinal tract (rectum), urinary tract, or blood and other body fluids. MODE OF TRANSMISSION :The means by which an organism transfers from one carrier to another by either direct transmission (direct contact between infectious host and susceptible host) or indirect transmission (which involves an intermediate carrier like an environmental surface or piece of medical equipment). PORTAL OF ENTRY : The opening where an infectious disease enters the host’s body such as mucus membranes, open wounds, or tubes inserted in body cavities like urinary catheters or feeding tubes. SUSCEPTIBLE HOST :The person who is at risk for developing an infection from the disease.

Gardner's Intelligences Assignment Example | Topics and Well Written Essays - 250 words

Gardner's Intelligences - Assignment Example The best way to depict Gardner’s Theory of Intelligence is as a wheel rather than in a linear manner. His theory of intelligence is broken up into the following categories: spatial, linguistic, logical-mathematical, bodily-kinesthetic, musical, interpersonal, intrapersonal, naturalistic, and existential. Spatial ability involves being able to visualize images such as puzzles using the mind. Linguistic intelligence is the intelligence of language. Everything dealing with words, reading, writing, etc. comes naturally to people with high linguistic intelligence. Logical-mathematical intelligence deals with mathematical computational abilities. Bodily-kinesthetic intelligence can be compared as being similar to athletic ability. People with good body-kinesthetic intelligence usually have good coordination as well as good reflexes. Musical intelligence coordinates to musical ability such as singing, recognizing tones, playing an instrument, etc. Interpersonal intelligence talks abo ut the ability of people to relate with one another and intrapersonal intelligence relates to the self-reflective behavior that we have within ourselves. Lastly, existential intelligence can be related to spirituality. Since there are so many aspects of intelligence, some of these are interconnected and it is possible to be intelligent in multiple areas. This theory also explains how people who are considered to have lower IQ scores could be gifted in other areas.

Strategic Role of Human Resource Management Assignment

Strategic Role of Human Resource Management - Assignment Example A good place to start this was in the business of home textiles, as the firm successfully established its first renowned brand in the home textiles market in Turkey. Earlier in 1990s, the firm managed to engage itself in the business of electronics after acquiring Vestel Electronics. Zorlu aimed further to expand by taking the plunge into the energy sector in 1996. After ten years, the firm started to initiate another business in the real estate. Today, in Vestel Electronics alone, Zorlu is employing more than 15,000 people, and having 1,050 sales points and 400 after-sales service centres. Having almost 50 companies, Zorlu has now become home to around 30,000 employees who manage to work with the company for the future of providing highly improved quality of life for all. Prior to the actual recognition of potential applicants who would make it through the entire recruitment process, the Zorlu Group is adhering to its policy to select the human resource having a heart to live in its core values. On its website for its Human Resource Policy, the firm states, â€Å"We expect every employee to commit to our group’s shared values† (Zorlu Holding, 2013). This shows that Zorlu would want to become effective in employing its corporate culture and strategy by making sure that the human resource has the adherence to its core values. After passing the tests, the successful applicants would proceed to series of at least 2 or 3 interviews with the HR or the executives in relevant departments who would initiate at some point a competency-based interview (Zorlu, 2009). Those who would make it all the way from the general tests to interviews proceed to offer stage. This is the final part of the recruitment process where the applicants would receive employment contracts if they accept the offer (Zorlu, 2009). This process is a clear indication of optimising the human resource’s potential contribution for organisational benefit (Compton et al., 2009). This also paves the

The Trail of Tears Essay Example | Topics and Well Written Essays - 2250 words

The Trail of Tears - Essay Example Many Indians also died while being forced to relocate, a sanitized way to refer to the ethnic cleansing of tribes which were formerly located in the area east of the Mississippi River. The Indian Removal Act of 1830 mandated the relocation of many tribes, predominantly the Cherokee Nation which allowed for a ‘whites only’ America in what constituted the majority of what was the U.S. at that time. The journey out of lands occupied by the Cherokee, comprising thousands of miles and known as the Trail of Tears, is but one example of the injustices suffered by the natives of America brought about by the U.S. government. This distressing episode in American history was not acknowledged by government officials and was not included in school books until somewhat recently. This discussion illuminates this despicable action by the U.S. government, the events leading up to the deadly, forced march, its effects on those driven from their homeland and the overall consequences of eth nic cleansing American style. Ethnic cleansing is an act that is now condemned by the U.S. when perpetrated in other regions of the world but is a morbid reality of American history, perpetrated and endorsed by the American government. It may be hard to imagine the government seizing your home and forcing you, your family, relatives, neighbors and friends to walk halfway across the country in the dead of winter but that is what happened to thousands of native peoples 170 years ago. The American government, established by the people and for the people on the concept of justice for all, subjugated these men, women and children by forcing them off their lands. Those that survived the mass displacement found themselves in unfamiliar territory, a daunting proposition for a people whose survival was entirely dependent on understanding every aspect of familiar territory. Today, the Trail of Tears incident evokes sympathy from the general public but at that time,

Revising this qualitative research paper Essay Example | Topics and Well Written Essays - 3500 words

Revising this qualitative research paper - Essay Example Exactly how the elderly cope with chronic illness, and how they develop their own self care strategies in response to those illnesses, is extremely significant: the impact of the disease can be attenuated by proper self care. In the lives of most elderly people, self-care not only can foster the individual to develop his or her potential under the limitations of disease, it can be helpful in keeping independence and initiative, enhancing the sense of control over health, and reaching the best state of physiological, psychological, and social well being (Connelly 1987). Given the significance of the area, one research question is particularly important: What are the experiences of self care in the chronically ill elderly The primary objective of this paper is to discuss the life experiences of self-care in this class of individual. First, I will provide a contextual background by defining self care and chronic disease, explaining the general significance of the issue, and then relating those concepts to the elderly living in Taiwan. Secondly, I will provide an evaluation of why the phenomenological research approach is the most appropriate qualitative research method, and offer a critique of the results of other studies on the subject. Finally, I will describe the steps that could be taken to conduct a qualitative study and propose why these steps are appropriate in answering the research question. Contextual Background Self Care. The concept of self care developments has been an area of concern in various academic departments such as medicine, nursing, psychology, sociology, and health education (Gantz, 1990). Each academic discipline has focused upon different aspects of self-care from its own perspective of what is important or significant. The following are viewpoints from medical, health education, and nursing perspectives are more directly related to nursing care, and further introduce the concept of self-care. In the field of medicine, Levin (1976) demonstrates it has long been believed that self-care is a process which operates in favor of one's health. Self care promotes health while it prevents, discovers, and treats diseases. It is considered a vital part of preliminary care in the nursing system. Vickery (1986) believes that self-care is constructive behavior and an individual's way to pay attention to medical issues. In other words, self care is a behavioral expression that focuses on medical problems or physical symptoms; and it also displaces nursing care obligations. Behavioural changes of patients are, for the most part, concentrated on following medical advice (Gantz, 1990). Health education coordinates individuals' regulative and corrective behaviors by making use of the education process and behavior-change strategies (Parcel, Bartlett, and Bruhn, 1986). For example, under applied stress or self-adjusting skills and self-handling behavior, correction skills help change living modes (Gantz, 1990), promote

The Structure and Development of Nigerian Economy Essay

The Structure and Development of Nigerian Economy - Essay Example The current president Umaru Yar'Adua came to power following a controversial election in 2007. The economy of Nigeria has always been dominated by Petroleum accounting for about 25 percent of GDP. 90 percent of exports consist of petroleum and related products and 70 percent of government revenue comes from Oil. But lately its dependence on oil is set to change due to the constant disturbance in the delta region making oil production difficult. About 65% of the population is engaged in agricultural activities. The Economic reform in Nigeria started in year 2000, but the growth has been very slow throughout the country. Corruption remains pervasive despite progress made by the Economic and Financial Crimes Commission. -The paper aims to examine the overall economic development in Nigeria after its independence. The paper looks in detail how far the natural resources in Nigeria like petroleum, oil and gas sectors has helped the economic development of the country. It will also do an analysis of whether Nigeria depends too much upon the oil sector which provides 95% of its export earnings, and how this factor has weakened its agricultural potential. What are the major factors that contributed growth of Nigerian economy as a whole and what are the driving forces of Nigerian economy What are the underlying weaknesses of Nigeria as a country How corruption in Nigerian governmental agencies has affected the growth of Nigeria in all spheres. Objectives: To evaluate overall economic development in Nigeria for the last 5years (i.e. GDP rates, inflation or deflation, interest rates, movement of cash flow; rate of the Unemployment; and macroeconomic performance of the whole country). To analyze the growth of the petroleum, oil & gas sector, how far this growth has affected government revenue & economic development of the country. To discuss the trend in unemployment rate within the last 5years and evaluate whether the petroleum & gas sectors has any impact on such trend. Analyze problems in development of the economy due to lack of attention of government in agriculture & rural areas. To evaluate the various initiatives taken by the Nigerian Government to tackle the issues that hampers the economical growth of the country. (Erhiawarien). Work Cited Index of Economic Freedom: 2008. The Heritage Foundation. 2008. 16 Apr. 2008. . Nigeria: General Information. MBendi Information for Africa. 23 Aug. 2006. 16 Apr. 2008. . Nigeria: Economy. 16 Apr. 2008. . Country briefings Nigeria: History in Brief. Economist.com. Business friendly. 15 Nov. 2004. 16 Apr. 2008. . Erhiawarien, Mercy. Master's Dissertation Proposal - Nigeria's NEEDS, an Analysis of the NEEDS Policy. 16 Apr. 2008.

Capstone Essay Example | Topics and Well Written Essays - 750 words

Capstone - Essay Example Special academic programs serve the purpose of arming nurses with tailor made skills meant to enhance workplace related competence. Upon acquiring the required theoretical knowledge, nursing students may demonstrate their ability to articulate the acquired skills in duties within actual healthcare facility settings. At this juncture, I will examine my professional and intellectual growth upon completion of the nursing program. A nurse is free to choose any project as long as it addresses practical, real world challenges using the knowledge and skills gained while pursuing their graduate program. A capstone project entails a paper and presentation which uses the nurse’s experience to address a particular challenge identified in a proposal. A capstone program aims to evaluate nurse’s ability to identify a problem, formulate a relevant research question, use correct methods to tackle the research question and identify how their knowledge relates to current scholars and stu dies. The nurse should also be able to demonstrate the ability to organize information, interpret significance, write a good prose and use evidence and example to develop his study. Capstone portfolio is a benchmark assessment for the program and provides an opportunity for assessment by multiple parties. It help an individual assess himself as a nurse and long time learner and professional (Huba and Freed, 2000) because after graduation, the individual is involved in a process of continuous reflecting, self-assessment and self-guided scholarly and professional growth. When information from your capstone portfolio is used, it provides a forum for assessment by employers or other people from whom the individual seeks specific opportunities. Assessment plan for capstone portfolio is comprehensive as there is minimum requirement (average grade point) to qualify for the program and other qualifications an individual is supposed to meet like the need to provide finger prints, check of cr iminal records and computer competency. Then in the course of the program there is constant assessment by instructor on the courses undertaken and grades earned in return. In other cases a nurse is expected to pass a certain specified course before they can be allowed to undertake another course. This could also apply in courses where one needs to pass in the theoretical classes before they can be allowed into the field for practical work or internship. Classroom experience provides a basic framework before you are allowed into the field which is used as a forum to assess how good one has gripped the concepts that were taught. Upon completion of the program, I have acknowledged importance of acquiring informed consent from clients during clinical and social care procedures. Professional conduct of nursing involves explicitly defined guidelines concerning ethical practices. In addition, the program emphasizes the importance of nursing professional conduct towards the cultural require ments in a nurse-client relationship. In my practical encounter with geriatrics patients, I have learned that clients may refuse to undertake certain clinical procedures, even if those procedures are beneficial to their wellbeing. Throughout the course, I appreciate the fact that clients have a right to decline treatment. As a nurse, I will only be able to administer clinical procedures after acquiring voluntary and informed consent from a patient. According to Heartfield and Andre (2011), this relates to

Understanding Effects Of Ethnicity In Afghan Culture Essay Example for Free

Understanding Effects Of Ethnicity In Afghan Culture Essay Ethnic differences prevalent in Afghanistan have had a great impact on peoples’ personal lives especially during interpersonal communication. As an Afghan citizen, belonging to the Pashtan ethnic group, born and raised in a multicultural society, I had to master the art of effective communication at an early age. Here in this paper, I will explain how my life has been impacted by ethnic differences in Afghanistan especially during interpersonal communication. I will explain how I communicate with my friends from my ethnic group, from other ethnic groups as well as foreigners living in Afghanistan. My paternal grandfather, a Push tan was a governor in Central Afghanistan while my maternal grandfather, a Tajik, was the Interior Minister and finance minister and my father was the Mayor of Herat City, in the west of Afghanistan. Afghanistan is situated in South-western Asia. It borders Iran, Pakistan and several other countries in Central Asia. The â€Å"Islamic State of Afghanistan† is Afghanistan’s official name. Kabul is the capital and the other two major cities in Afghanistan are Herat and Kandahar. More than three quarters of Afghanistan’s population inhabits rural areas. The literacy level in Afghanistan is very low and it is among the world’s countries with small economies(Hussain 34-35). My ethnic group, Pushtun, is the major ethnic group in Afghanistan accounting for almost a half the population (42%). Tajiks account for 27% Hazaras 9% Uzbel 9% Aimak 4% Turkmen 3% while the other ethnic groups account for 4% of the population. As a result of the diverse ethnic groups, Afghanistan has been adopting various language policies in a bid to foster national unity. For instance, in 1992, the communist regime fell due to constant fighting which arose as a result of issues such as language policy. Linguistic differences made various factions fight each other. Consequently, between the year 1992 and 1996, Afghanistan’s national anthem was changed from Pashto language to the Dari(Hussain 40-44) The 2003 Draft Constitution in Afghanistan saw the Pashto and Dari languages become the official languages during the Draft Constitution’s amendments of Afghanistan’s language policy. The constitution made provisions guaranteeing all languages as equal. In today’s world, most countries strive to preserve its people’s culture as well as the language. Afghanistan has adopted the Assimilation Language Policy, which is aimed at fostering national unit by having a single national language. Pashtu is the national language of Afghanistan(Hussain 35-39) In Afghanistan, bilingualism is very common. Most people, especially literates can write and speak in at least two ethnic languages. As a child, I acquired two ethnic languages. By the time I went for my primary education, I could speak a few Dari words and phrases in addition to my mother tongue, Pushtan. When I joined school, I learned the Dari language which is taught because it is the national language. When people become competent in two or more languages, they tend to use both languages in interpersonal communications. This results in switching between codes and mixing phrases from two different ethnic languages. Code switching is the use of words or phrases from two distinct languages or dialects in interpersonal communication. Code mixing entails the use of various words or phrases. When participants code-mix, they learn to relate what is altered by the speaker during a speech activity with the intended meaning as well as learning to compare what is spoken with what they know(Wood 67). In Afghanistan, people may code switch consciously or unconsciously. When a person code switches unconsciously, it is because s/he has gained competence in the two languages. Thus, one will switch between the languages and may not intent any communicative effect on the listeners, although the listeners may achieve an effect depending on how the speaker switches or mixes phrases. Conscious switching or mixing between different languages entails the speaker’s conscious effort. The speaker decides where to put a certain word or phrase with the aim of achieving a certain communication effect (Julia 30). Whenever I am with my Pushtan friends, we at times switch between the Pushtan language and the Dari language. At times, we do this unconsciously without putting into consideration the communication effect it will have to our listeners. Competence in both languages enables us to know where, when and how to mix the codes and switch between the two languages effectively. After all, we have spoken and written in these languages since childhood. In Afghanistan, people switch between languages for a number of varied reasons. For instance, whenever I am with my Pushtan friends and a band of people from say Dari whom we may detest and look down upon joins our band, we will code switch and code mix intentionally. We do this in a bid to make them feel unwanted. Occasionally, some of us will mix some Pashtun words with the Dari language. Infact, a great percentage of the words and phrases used in the speech may constitute Pashtun words. Normally, during most interpersonal communications, everyone wants to participate and this entails understanding what the other participants say so as to respond effectively. Since we withhold certain information from them by code switching, this makes the Dari speakers not participate in the speech act. Consequently, some of them may opt to leave the band while the stubborn ones may remain behind. Nothing irritates like people breaking into laughter and you are left wondering what amused them. One can even be made to think that he is the subject of mockery. Thus we may code switch so as to eliminate those we don’t want in our band (Jacobson 54) Our group may also code switch so as to make other groups of people feel appreciated. For instance, whenever we are with our friends from other ethnic groups, some of my friends who have mastered a few phrases and words from the languages will mix them with the Dari language. This makes them feel accommodated in our band. They feel that we appreciate their languages which are deemed to be inferior simply because they are not the official or national languages in Afghanistan. During interpersonal communication, everyone wants to be a part of the speech event. Consequently, our friends will feel motivated to participate because we acknowledge their presence. In addition, whenever I am with my Pushtan friends and we encounter Dari speakers who are not competent in Pushtan, we choose to use the Dari language in a bid to accommodate them. During a speech event, people tend to accommodate the other speakers. This is very crucial for effective communication. Imagine a situation where you speak to someone in, say, Dari, and he responds in Pashtun. Will you continue speaking in Dari? Of course not you would rather opt to switch to Pashtun if you are competent in it so as to avoid communication barriers. Language differences in Afghanistan can lead to communication barriers and so people have learned to accommodate others during a speech event by switching to the language used by other participants (Giles and Coupland 52). During a speech event, we may change our styles from time to time. Some of the reasons which make our band change styles during interpersonal communication include the topic being discussed, the participants in our band, and the motives/intentions of our band and so on. So we accommodate other participants by adjusting the number of times we switch between languages and strive to minimize the number of switches depending on the person we are speaking to. The accommodation is applied in our day-to-day speech events. In fact, some of my Dari friends who are not competent in Pushtan have mastered a few Pushtan words and phrases. Whenever we are conversing, they may mix a few Pashtun phrases with Dari phrases in a sentence. They do this so as to please us. They want us to think that they recognize and appreciate our language. As a matter of fact, some of them do this sarcastically; nothing irritates a Pashtan speaker than to hear a Dari speaker or any other speaker use a Pushtan word or phrase of which he or she does not even have the slightest idea of its meaning. Worse still, some of them may even use the wrong word order. I once lived in Hawaii and learned a few Hawaii words. When I visited the United States, I could hear the Americans switch to the Hawaii language. Some Americans could even mix spiritual phrases and words with English. What irritated me most was the fact that the Americans were not competent in the Hawaii language, yet they could dare mix Hawaii spiritual words and phrases of which they did not even know the meaning. I consider this as a kind of theft and a slap on the face to the Hawaii language. People should respect other peoples’ language especially spiritual words and phrases. In addition, Afghan’s may also code switch because they feel that they cannot express themselves well in a certain language. They feel that they lack certain words or expressions from a given language and that another language may have a ready word or expression for the message they want to convey. Whenever I am speaking with my Pashtun friends, who understand the Dari language, I will not bother much to think for a word in Pashtun when I have a Dari word or phrase for it. Most people will sometimes find it difficult to express themselves in their mother tongue. To some people, expressing oneself in an official language is much easier since it is the language they use most of the time, thus, they always have ready words and phrases. Most people agree that it is easy to express oneself in Dari, the national language simply because they use it more often and they may lack the appropriate words in their original language. Afghans view code switching to be beneficial during interpersonal communication although this will depend on the context or situation in which it occurs. This holds true, especially when a speaker encounters problems expressing himself in a particular language and he/she is competent in another language which his speakers are competent in. Thus, a speaker will break the communication gap by inserting phrases or words from the language his participants understand. Ethnicity also affects communication styles and strategies in Afghanistan in that, people from different ethnic groups have differences in social etiquette, customs and protocol. In Afghanistan, there are some common customs and protocols among the different ethnic groups, which affect interpersonal communication. For instance, men and women should not make eye contact. Men should not prolong their eye contact with other men and when they do, they should do so only occasionally. This custom creates a communication barrier in that communication between men and women is not effective since women are not allowed to speak directly to men. If a woman speaks directly to a man, she is being disgraceful and lowering her dignity. This greatly affects my life since women in our country are deprived of rights of expression, which implies that our mothers and sisters, who are the backbone of our nation, have no direct communicative role to play in the society. This implies that men and women in my country have to employ different styles and strategies in both verbal and non-verbal communication. In order to ensure that they preserve their cultural values, mixing between genders in my country is not freely allowed and free mixing only takes place within families. In places of work, in offices, and businesses or at institutions of learning, both higher and lower, both men and women must respect and maintain each other’s honor. They must also adhere to their culture without putting into consideration the impact it will have on interpersonal relations. Consequently, this has led to poor interpersonal relations in public places, which has led to increased war and conflicts among individuals, groups of people and ethnic societies. These have led to men dominating the country. Since they are the only ones who have a say, they have gone ahead and enacted and enforced laws and regulations which undermine their women folks and children who are regarded as inferior members of the society. Interactions and relations between individuals have also been adversely affected especially in institutions of learning. Foreign students who join universities in Afghanistan are faced with major challenges. To start with, most of these students come from ethnic backgrounds where women and men are regarded as equal. Consequently, they are forced to learn and to read the rules and ensure that they abide by them. This has led to students’ academic performance being affected since they spend a lot of time adapting to cultural changes. Besides eye contact, which is a non-verbal communication style, other types of non-verbal communication are also affected. Signals are also affected by ethnic differences. People send signals to convey messages. Sending of signals has been affected by ethnic differences in that people may send the wrong signals during the process of communication. Since women are not allowed to look at men in the eyes, this may pass the wrong signals to foreign men who have not mastered Afghanistan culture. They may think that the women are shy and may consequently tease them or misunderstand their intentions. In addition, since men and women are not allowed to shake hands, a misunderstanding may arise when an Afghanistan man or woman declines to shake hands with a foreigner who is not aware of the cultural values in Afghanistan. As a result, the communication process among different ethnic groups in Afghanistan has not been effective. The handshake is the most common form of greeting used in Afghanistan, Placing one’s hands over their hearts and nodding slightly is also another form of greeting. Foreigners can misunderstand this and a wrong signal can be sent probably signaling that someone is in love or in shock depending on how placing one’s hands over one’s heart implies in one’s culture. Symbols are also another form of non-verbal communication used. Symbols can be used to represent or express information. For the process of communication to be effective, the transmitter needs to employ both verbal and non-verbal forms of communication because they supplement each other. Ethnicity in Afghanistan has affected interpersonal communication in that cultural values have made the use of symbols ineffective by making them fail to communicate the intended information. Whenever I am socializing with the women folks in Afghanistan, I do not get their message right since they do not use symbols appropriately in a bid to uphold their cultural values. Men are supposed to dominate all interactions including interpersonal communications When a Turtumani person is speaking to a Baluchi speaker, one has to use Dari, which is the official language. The two language speakers have different cultural values and backgrounds. The problem may arise if one of the speakers say the Baluchi speaker, is illiterate and does not understand the national language. Thus, the two speakers will need the assistance of an interpreter. If the interpreter is not competent in both languages, a communication breakdown may arise. Most literate Afghans have learned Social and Humanistic languages and have leaned that each ethnic group is unique in and that no ethnic group should be considered superior than the other. Language reflects a peoples’ culture. Verbal communication entails use of well-constructed sentences with a correct word order. According to linguists, each language is unique in its own way and no language is deemed to be more superior to other. Thus, each Afghanistan ethnic language whether used as a national or official language contains complex structures. Each ethnic language has its own unique way of tense formation. Since the literacy level in Afghanistan is very low, communicating with people who are not learned in Afghanistan has posed a great challenge for me and my literate friends. I recall with nostalgia an incidence where my best Friend, Pierre picked up a fight with an illiterate Dari speaker as he tried to convince him that all languages are equal. In conclusion, ethnicity affects interpersonal communication in Afghanistan in that certain ethnic communities look down upon others. Some communities feel that they are greater/superior than others simply because they are considered to be bestowed with more natural resources than the others. Consequently, a communication gap may arise between the two. For instance, Dari ethnic groups and the Pashtans perceive themselves to be superior to other ethnic groups like Turkmen or Aimak ethnic groups. This is because they are a majority groups in the country’s population and their languages are recognized as the national and official languages. Each ethnic group in Afghanistan has a specific vocabulary, which it uses during the process of communication. For instance, the Pashtans have a specific and unique vocabulary, which they use. These cultural vocabularies hinder communication when one is speaking to members of a different ethnic group who do not have competence in the Pashtan language. As a result, Afghans should learn to embrace their diverse cultures by learning to cope with the challenges they encounter due to ethnic differences on their day-to-day activities. Afghanistan has been through many calamities and disasters, or instance, landmines and explosions. Schools have also been shattered, hospitals and roads demolished not to forget violence against women and drug addiction among the youth. These problems can be minimized by effective interpersonal communication among differing ethnic groups or parties.

How does Edger Allan Poe Use Language to Create a Sense of Drama Intention Essay Example for Free

How does Edger Allan Poe Use Language to Create a Sense of Drama Intention Essay The Tell Tail Heart, by Edger Allan Poe, is a novel in which tension and expectation play essential roles to the readers experience. The audience, generally well educated widely read adults, would appreciate this novel as a recollection of a clearly insane man. In order to tell you the whole story Poe has written somewhat of an early psychological thriller, creating a mental portrait of a mad protagonist, who details the killing of an old man, and later hears his victims relentless heartbeat. The opening sets up a contrast of sanity versus insanity, creating a psychological chaos that enraptures the reader. Drama intention is portrayed through a variety of ways, all working cohesively with one another to create an over all sense of embossed insanity and powerful emotion. The way in which the opening is written gives the reader an immediate clue to the mental state of the protagonist. The very first line; True! nervous very dreadfully nervous I had been and am; but why will you say that I am mad? uses all three tenses within one shortened period. This reflects the narrators excitement, suggesting that his mind is jittery, jumping about with different thoughts and ideas. An elevated use of punctuation reinforces this effect, as it means the text does not flow, creating sentence fragmentation, allowing the reader to comprehend the elevated mental state of the protagonist. It is not yet made clear to the reader as to why the narrator is excited in this manner, he appears to be worked up about something, causing the reader to grow curious and excited themselves about the prospect of finding out what is causing his fuss. Poe has used the tactic of withholding information strongly within the first paragraph, causing the monologue to become somewhat of a gradual revelation. This allows Poe to hold the reader in suspense, consequentially creating a heightened level of dramatic tension. Written in a first person narrative, it is made very clear that the monologue is of the form of a speech to the reader. This effect is achieved by the extensive use of punctuation and colloquial terminology. As it is a monologue, there is a suggestion or effect that he is confessing his thoughts to the reader. This means that the piece is almost as if we can see into the mind of the protagonist. Allowing the reader to see a unique view of the thoughts and feelings of another. The form of the text is not over zealous or important, however the contrast of the content and the form is very clear. The piece is written in standard, respectable paragraphed prose, contrasting the disturbing and gruesome content of the novel. The language employed, and the literary devices it is used within, is the primary way in which Poe has succeeded in creating this suspenseful piece. Punctuation is used to great effect, embellishing the sentences to create the narrative confession of the protagonist. Extensive use of exclamation marks, hyphens, and semi colons are all relied upon to create sentence fragments and colloquial, broken text. The reader is given an immediate sense of excitement and instability; in True! nervous- very very dreadfully nervous. This suggests that the protagonist is jumpy and in a chaotic mental state. As an opening this proves to be attention gauging, as the reader is unaware of the motive for excitement. This is extended throughout by a heightened use of fragmentation through hyphens. The line, Sharpened my senses not destroyed not dulled them reiterates the form of a monologue, reinforcing the idea of speech to the reader, using the sentence fragment as a chance to find some self affirmation. Therefore the reader is allowed to see the within the mind of the criminal, giving them a unique insight to the way he thinks allowing greater involvement and understanding from the reader. This is an unlikely experience as the protagonist shows signs of mental instability and therefore would create a very interesting subject for the reader to asses from a psychological point of view. An extensive vocabulary and heightened lexis is employed throughout the piece, suggesting that the piece is aimed at the well educated adult. The majority of the novel is comprised of Standard English, with a small number of colloquialisms spread throughout, allowing the protagonist to appear both educated and well-spoken. This creates an interesting contrast to his actions, as it is not the norm to have well educated, (supposedly well judged and reasoned) people committing a very irrational act such as murder. The monologue is written in the form of a conventional novel, but primarily in the form of a narrative first person. Hints of confession to the audience are found, intertwined with the use of direct address, with colloquial terms such as Ha! and the use of rhetorical questions, for example why will you say that I am mad? Poe has used these devices to thoroughly involve the audience within the piece. The result of this is that the reader is manipulated to feel like part of the story and therefore feel the tension created at a greater effect. Poe has employed various forms of imagery within the piece. He describes that the hinges creaked on the old wooden door. This is a little clichà ¯Ã‚ ¿Ã‚ ½d however acts very successfully in creating a picture within the mind of the reader. This is done by almost sub-consciously relating back to childrens stories, where an old creaking door would make the entrance to a spooky castle in which an evil witch lived. This very definite image of the eerie or spooky, reinforces that the novel is somewhat of a refined horror. Creaking doors are often used to create a dramatic atmosphere, and Poe has clearly played on this link and used it to his advantage to create a scary situation for the reader. Animal imagery, coupled with an extended metaphor is also used to great effect. It is suggested that the old man that is to be killed is in possession of an evil eye. This eye becomes the protagonists excuse for killing the man, and so it is capitalised upon as a reason. This develops into an extended metaphor when it is referred to as a vulture eye and later, it is suggested that his eye resembled that of a vulture. A vulture is an animal commonly associated with evil and malice. This provokes a similar reaction or opinion of the old man from the narrator, however the reader is still left considering the sanity of the protagonist, and therefore is more reluctant to hold the same opinion as him over the justification of killing the old man. The irrational killing about to happen is used to put the reader on edge, creating intense suspension and a heightened expectation of the approaching events. Clichà ¯Ã‚ ¿Ã‚ ½s provide an interesting platform on which Poe entertains the reader. My blood ran cold, provides a very clear sense of the emotional situation of the protagonist. This allows us to observe the effect that the eye has on the narrator. Blood ran cold suggests fear and apprehension, as this is a very human emotion, the reader has a rare chance to sympathise with the protagonist. This is somewhat ironic as the narrator is very far from the stereotypical hero, and yet the reader is ready to find an appealing quality in the character. In order to interpret the piece properly the reader must pay close attention to both the syntax and the repetition of language, used conjunctively to create a dramatic effect. Object there was none, passion there was none is a primary example. The repetition of none creates a very distinctive rhythm, whilst the double use of five syllable sentence fragments forms a very recognisable syntax. In this case it creates a sense of ruthlessness and suggests that the protagonist will stop at nothing in order to achieve his goal. Repetition of closed in closed closed creates emphasis on the words, displaying to the reader his self affirmation that his actions are good. This is reinforced by the use of oh so cunningly making it clear that (in his opinion) he is very skilled at what he is doing, and consequentially commending his efforts. This is further enhanced by the narrators egocentricity. Use of I is extensive throughout, (which is partially natural during a monologue) however, it is used to such an extent that the reader is led to believe that the protagonist is almost obsessed with himself and his own actions, reiterating the previous suggestion of psychological instability. The author has included various forms of irony within the novel. The narrator is seen inquiring how he (the old man) had passed the night explaining how he asks the old man how his night was even though he already knows, seen as he was there and watching him in his sleep. This involves the reader as they feel as if they are let in on a secret (seen as they know that the narrator was with the man last night) making the reader feel involved as they are aware of a secret of which another character is not raising tension and expectation. Further use of direct address to the reader, is that narrator suggests to the reader that you fancy me mad. This forces audience intervention, we are expected to assume, or are at least are accused of assumption that the narrator is mad. This means that the audience are forced to participate, further involving the reader within the story. By this statement Poe has grouped the reader with the rest of the characters within the novel, suggesting they are a collective of people who doubt his sanity. This is in fact true as the protagonist is clearly insane. Syntax plays a key role in the way in which this novel is read. It is clearly set, and easily recognisable throughout the text, varying in both tempo and patterning. Definite patterns in language are used; I heard all things in the heaven and in the earth. I heard many things in hell. creating a very obvious rhythm in which the words are read, also further enforcing the very bleak and ruthless appearance to his actions. The Tell-Tale Heart, a horror story of crime and murder, can easily be recognised as a heavily dramatic novel. Poe, In consequence to the timing in which it was written, has created a strongly macabre piece, that in its day was probably very horrific and shocking. The way in which society has adapted to accept more and more gruesome revelations means that this tale may not be so shocking to the modern day reader, but was quite a feat in its time. It is however, still evident that the novel, in particular the opening, contains many devices employed in conjunction with one another to create a sense of drama intention. This is used to great effect, causing the reader to appreciate the dramatics of the novel, whilst becoming deeply involved with the plot.

Selective Oestrogen Receptor Molecules (SERM)

Selective Oestrogen Receptor Molecules (SERM) Lucy Perry Perry Pharma Development Pipeline Introduction: Perry Pharma Research Development (PP-RD) has been investigating Selective Oestrogen Receptor Molecules (SERM) for potential development that will be effective in both breast and uterine cancer as part of its drug pipeline. Early clinical testing of PKWT and PKWX, for which PP holds Australian patents (66633 –PKWT and 44455 – PKWX) for, indicates significant improvement in their selectivity, clinical outcomes and safety profiles when compared to the current SERMs. Thus, providing an assessment of the development considerations including efficacy, safety, therapeutic indications and potential market share would aid PP in making decisions concerning the development of these molecules. This information is now vital due to a potential infringement of patent 66633 – PKWT, by HCH who manufacture ‘Tamax’, and are about to launch the successor ‘Pro-tam’. PP-RD has analysed samples of ‘Pro-tam’, which has been identified as PKWT. Because of the impending launch, PP-Legal is including recommendations for dealing with this infringement within this review. Selective Oestrogen Receptor Modulators Cancers that grow in response to oestrogen are termed ‘ER-positive’. Oestrogen receptor positive cancers growth is modulated by oestrogen binding at the oestrogen receptor (ER). These ER are located in breast, bone, central nervous system and uterine tissues. SERMs action in the body is through agonism or antagonism at the ER, leading to both positive and negative effects depending on the tissue site. Antagonism of the ER and blocking of the action of oestrogen in a specific tissue such as the breast or uterus is responsible for anti-cancer action of a SERM (Fabian 2005, Maximov 2013). PP is interested in developing PKWT and PKWX for these ER-positive cancers. Treatment of ER-positive cancer: ER positive cancers are one of the most common forms of breast cancer subtype (ACS 2014a). SERMs are used as primary, combination or adjuvant therapy for cancers expressing the ER receptor (Yilmaz 2013, ACOG 2014, Sledge 2014). Compound choice is dependent on the patient population, and the associated treatment period may last up to 10 years (ACOG 2014, Sledge 2014). In uterine and endometrial cancers SERMs are less utilized, (Burke 2003, ACS 2014b,c). Tamoxifen has shown some efficacy, however the Product Information does not list endometrial and uterine cancer within the indications; these are included in the Precautions section (eBS 2014, ACS 2014b, c). Highly selective SERMs are being developed to reduce off target action and improve safety profile, through exploiting the receptor subtypes. (Jordan 2004, Maximov 2013). However biological agent based therapies for breast and uterine cancers (Fabian 2005) make the future for SERMs unclear. Issues in the development of PKWT PKWX: Indications: PP needs to be strategic in the selection of indications to pursue. This will dictate not only the size of the treatable population and the amount of clinical data required for the registration dossier but also potential return on investment. It will also play a significant part in whether the compounds are listed on the Pharmaceutical Benefits Scheme (PBS) PKWT and PKWX both have shown high selectivity as well as good safety and clinical outcomes in women of all ages compared to current SERMs and establish these compounds within an already crowded market. First, PP can position development of a ‘one tablet for both breast and uterine indications for all ages’. Although this will mean a complex and costly clinical development plan, it entails a potentially a larger population to treat due to the wider indications. Second, PP may take a different approach aiming for a specific indication such as the ER positive breast cancer in post-menopausal women, but limiting the treatable population. It is worth noting importantly that there are no SERMs with approved indications for uterine or endometrial cancer, despite phase II trials (Munster 2006), which indicates a potential gap in the market. PP could launch the first SERMs indicated for ER-positive uterine cancer. PP will need rates of ER positive uterine cancer to determine the available market to ensure return on investment and determine any potential competition through patent searches. The third option is to enter the market leveraging the structural novelty of PKWX active metabolite, with improved outcomes and safety. This may provide a compelling case for prescribers to switch treatment options. Efficacy PKWT and PKWX have both shown good clinical outcomes for both breast and uterine cancer. They are also highly selective, which is an important consideration so that off-target action is minimised which responsible for the safety profile of the current SERMs (discussed in Safety section) A consideration for prescribers is the secondary effects of oestrogen treatment. SERMs have been shown to be effective against osteoporosis, keeping lipid profiles favourable, aiding in the reduction in symptoms of menopause, cardio-protectivity and risk prevention of cancer (Maximov 2013, Munster 2006, Pickar 2010). PKWT and PKWX must show some of these positive secondary effects to be competitive. Prescribers will not switch to SERMs which can lead to the same outcome but leave a patient worse off e.g. from loss of bone minerals or exacerbation of menopausal symptoms. Length of treatment with SERMs such as Tamoxifen can be up to 10 years to ensure optimal clinical outcomes for patient (ACOG 2014). PP needs to investigate whether PKWT or PKWX requires the same significant period of treatment to achieve clinical outcomes. Safety Due to the pharmacological action of SERM’s acting as either agonists or antagonists at the ER, negative secondary effects can occur. SERMs safety profile includes development of endometrial abnormalities, increased risk of endometrial cancers, pulmonary venous thromboembolism’s and increased incidence of stroke (Pickar 2010, Qin 2013). PKWT PKWX have been found to have better safety profiles, due to the higher selectivity for breast and uterine ER’s, both acting as antagonists at these receptors. Tamoxifen has agonistic properties at uterine tissue which is linked to its use increasing the risk of uterine/endometrial cancers (Yilmaz 2013). However no information has been provided on the adverse event profile known to date and no animal data on long term use associated with treatment length of current SERMs. Market Share and Market Advantage: ‘Tamax’ is a recognised brand, (first patented 1978) with an established market; it is now the preferred treatment for breast cancer in pre-menopausal women. ‘Pro-tam’ which has reportedly an improved safety profile over the originator ‘Tamax’, already has an established brand and market. PP may become a direct competitor and will require a significant point of difference to change prescribing habits of clinicians. The market advantage within the breast cancer treatment arena may be the improved safety and clinical outcome; however PP needs to consider whether it wants to produce a ‘me-too’ compound. As a SERM to treat uterine cancer specifically, it would be a first. PP should consider pursuing compounds specifically into this new market, especially if there is the added advantage of treating breast cancer. Again PP should consider the structural novelty of the PKWX metabolite as well as improved safety and clinical outcome as a market advantage to attract clinicians and gain some ground in the ER-positive breast cancer market. Regions in which Tamax has been launched needs to be obtained, so PP can determine if there are any new markets, and if there are regional specific factors such as the PBS. Pricing strategy and treatment indications will be important in these markets. Investment Costs As part of the review process there needs to consideration of the level of return on investment. PP need to be sure that if development goes forward they have a treatable population and potential to gain market share or market advantage. PP may wish to consider attempting to out-license the compounds if the development costs prove too much of an investment. Legal: PP-Legal has flagged potential PKWT patent infringement by HCH. The associated legal proceedings may add significant costs to the development budget and also effect development timelines. ‘Pro-tam’: Potential Patent Infringement? HCH is launching ‘Pro-tam’, a prodrug that is claimed to be metabolised into ‘Tamax’. PP-RD have analysed the metabolite and found it to be PKWT. PP-Legal advises pursuing this as a potential infringement by HCH on the PKWT patent and to ensure appropriate legal action is taken to avoid any adverse impact on further development of PKWT. PP-Legal have suggested undertaking the following steps: Review the ‘Pro-tam’ priority date to ensure that it is dated after the PKWT priority date (25 April 2002). If the ‘Pro-tam’ patent does have a priority date prior to 25 April 2002: PP-Legal will review the ‘Pro-tam’ patent to determine any grounds to challenge its validity or navigate around the patent. Applying for a patent on PKWT for uterine cancer. This will require negotiation of a licensing agreement with HCH. PP transfers its efforts to the development of the more novel PKWX. If the patent for ‘Pro-tam’ was lodged after the priority date for PKWT, PP has grounds to pursue patent infringement and attempt to block the ‘Pro-tam’ launch by lodging a request for an interlocutory injunction. This will allow PP to restrain the allegedly infringing actions by HCH until settled in court (IP Australia 2012). The justification would be based on the ‘Pro-tam’ patent not meeting the novelty criteria as the chemical structure of ‘Pro-tam’ is listed as part of the PKWT claim scope (IP Australia 2012). HCH legally can patent the prodrug, but at the point of metabolism, the PKWT patent is infringed. PP-Legal have previously determined PKWT does not exist in published prior art. A patent on a prodrug and its metabolites is only valid if all conditions of patent validity are met. The ‘Pro-tam’ active metabolite structures should therefore be captured in the claims. If the PKWT structure is not listed and the PP-RD can provide evidence that PKWT is the active metabolite, there are grounds to claim falsification of aspects of the patent, as HCH has not disclosed all claim details into the public domain, thus invalidating the patent (IP Australia 2012). Here the emphasis is on HCH proving the case otherwise. PP-Legal suggests creating a further portfolio of surrounding patents for maximum protection of PP intellectual property and allow for further development of the SERM pipeline. The ‘Tamax’ patent has since lapsed, however, for completeness, PP-Legal have provided potential actions for PP to still patent PKWT if the Tamax patent was still valid. The original patent claimed a single isomer structure, which is not PKWT, nor was it described as racemic. The existence of other isomers was not common knowledge at the time of the patent application so HCH were likely unaware that the structure listed in the claim scope had isomers. Between 1996 2000 journal articles were published discussing the discovery of isomers of compounds that may confer improved efficacy and safety profiles. Despite these articles being in the public domain, HCH did not move to patent any potential isomers of ‘Tamax’. If a compound is described as a racemic mix in the aspects and that patent is challenged, court rulings in previous legal cases have stated that it is considered common knowledge that racemic mixtures may contain isomers with different properties and that it is obvious to try to separate these. Considering this information, PP could move to patent the PKWT isomer, on the basis that Existence of different isomers of compounds was not common knowledge at the time of the original ‘Tamax’ patent so the argument of obviousness that the patent would cover the PKWT isomer cannot be made by HCH (IP Australia 2012). If HCH had claimed a generalised formula for ‘Tamax’ type compounds, PP would be infringing (Harris 2013). Information on differences in efficacy and safety of undiscovered isomers has been in the public domain since 1996 and HCH still did not move to patent any isomers. Separation of isomers is possible by skilled practitioners since technological advancements have occurred. Conditions of patent validity can be met by PP – PKWT is novel as it is not described in prior art, it is inventive in that it requires a person skilled in the art (i.e. not obvious) to separate the isomers and it is potentially useful in treating disease (IP Australia 2012). Development Recommendations: PP needs to consider which indications to pursue –as it will affect the size and cost of the clinical development programme. The improved clinical outcome and safety, as well as selectivity, can provide market advantage in both indications. However, a breast cancer ‘me-too’ drug may not be successful in obtaining a PBS listing which is crucial to success of a medicine in the Australian market. The PKWT patent infringement proceedings may affect development schedules and add significant cost. Whereas PKWX has a novel structure that is not subject to patent infringement, so this may be the better compound to pursue to avoid the legal route Word Count 2118 References American Cancer Society (2014a) Breast Cancer http://www.cancer.org/> (Accessed Aug2014) American Cancer Society (2014b) Uterine Cancer http://www.cancer.org/> (Accessed Aug2014) American Cancer Society (2014c) Endometrial Cancer http://www.cancer.org/> (Accessed Aug2014) American College of Obstetricians Gynaecologists (2014) Committee Opinion – Tamoxifen and Uterine Cancer. www.acog.org> (Accessed Aug2014) Burke TW Walker CL (2003) Arzoxifene as therapy for endometrial cancer Gynaecologic Oncology 90 (2003) S40–S46. (Accessed Aug2014) eBS (2014) TGA Nolvadex Product Information. Astra Zeneca 2013 https://www.ebs.tga.gov.au (Accessed Aug2014) Fabian CJ Kimler BF (2005) Selective Estrogen-Receptor Modulators for Primary Prevention of Breast. CancerJ Clin Oncol 23:1644-1655 (Accessed Aug2014) Harris, T., Nicol, D., Gruen, N. 2013 Pharmaceutical Patents Review Report. Commonwealth Government of Australia.http://www.ipaustralia.gov.au/pdfs/2013-05-27_PPR_Final_Report.pdf> (Accessed Aug2014) IP Australia (2012) Pharmaceutical Patents Review: Background issues and suggested Issues Paper. Commonweath Government of Australia www.ipaustralia.gov.au/pdfs/Background_and_Suggested_Issues_Paper_PharmaReview.pdf> (Accessed Aug2014) Jordan VC (2004) Selective estrogen receptor modulation Concept and consequences in cancer. Cancer Cell Volume 5, Issue 3, p207–213. (Accessed Aug2014) Maximov PY,Lee TM,Jordan VC (2013) The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol.2013 May;8(2):135-55 (Accessed Aug2014) Munster PN (2006) Arzoxifene: the development and clinical outcome of an ideal SERM. Drug Evaluation March 2006, Vol. 15, No. 3 , Pages 317-326. (Accessed Aug2014) McMeekin DS, Gordon A, Fowler J, Melemed A, Buller R, Burke T, Bloss J, Sabbatini P (2003) A phase II trial of arzoxifene, a selective estrogen response modulator, in patients with recurrent or advanced endometrial cancer. Gynecologic Oncology 90 (2003) 64–69. (Accessed Aug2014) Qin T, Yuan ZY, Peng RJ, Zeng YD, Shi YX, Teng XY, Liu DG, Bai B Wang SS (2013) Efficacy andtolerability of toremifene and tamoxifen therapy in premenopausal patients with operable breast cancer: a retrospective analysis. Curr Oncol, Vol. 20, pp. 196-204; (Accessed Aug2014) Pickar JH, MacNeil T Ohleth K (2010) SERMs: Progress and future perspectives Maturitas Volume 67, Issue 2, Pages 129-138, October 2010 (Accessed Aug2014) Sledge GW, Mamounas EP, Hortobagyi GN, Burstein HJ, Goodwin PJ Wolff AC, (2014) Past, Present, and Future Challenges in Breast Cancer Treatment Journal of Clinical Oncology, Vol 32, No 19 (July 1), 2014: pp 1979-1986 (Accessed Aug2014) Yilmaz S,Gà ¶nenà § IM,Yilmaz E (2014) Genotoxicity of the some selective estrogen receptor modulators: a review. Cytotechnology.2014 Aug; 66(4):533-41.(Accessed Aug2014) Personal Reflection Starting this assignment I had no real knowledge of SERMs- I had a basic understanding of the use of tamoxifen so building background knowledge was a prompt learning curve. However, such events are to be expected in all professional practice and simply enable improvement. When I think about the writing and the researching of this assignment, I can say that I found the intellectual property section the most challenging and intellectually stimulating area, as it resonated with my detail oriented nature and love of deconstructing/reconstructing events and processes. I enjoyed the researching of case law and the practicalities of patents. I always enjoy doing the literature searches and review of papers, and the chance to delve into the legal terminology pushed me outside my comfort zone. The drug development side of the assignment was not so interesting to me. I would put this down to the word limit not really allowing for much exploration of the area. I would have liked to explore market share and the epidemiological basis and strategy of selecting an indication/s for these compounds in a much more detailed review. Because of my work sits strongly in the population health area, this early end of the development pathway is not really something that I am asked to consider often. However from the viewpoint of building a personal knowledge base and being able to provide answers to my direct reports regarding the drug development process in a more holistic manner, this assignment has been of help. Search Strategy Keyword Wildcard Search: PubMed Google Scholar SERM, oestrogen receptor modulator, ER breast cancer, ER uterine cancer, ER endometrial cancer, tamoxifen, hormonal cancer, Obtained literature centred on these wild card searches. Reviewed the literature to build a knowledge base to write the first half of the assignment. Reviewed 9128 course notes to finalise ideas. Keyword Wildcard search: Google Google Scholar Pharmaceutical Patents, enantiomer patents, isomer patents, isomer legal cases, patent portfolios, patent law Australia, pharmaceutical patent cases Australia, intellectual property law Australia, Obviousness, inventiveness. Obtained literature and websites centred around these wildcard searches, Reviewed the literature to build understanding of IP law and previous case law. Referred back to Australian IP law to check proposal was sound. Reviewed 9128 course notes to finalise ideas.

Were Romans Obsessed with Violence? :: Ancient Rome Roman History

Were Romans Obsessed with Violence? In many modern books written about Ancient Rome and her people, the Romans are often portrayed as brutal and unforgiving people who enjoyed violence and thought it amusing to see people being injured and killed to the point of obsession. It is my aim to establish whether this classification is justified or if it is simply an exaggeration of what a small group of people enjoyed. While it is known that in Rome there were gladiatorial fights, public beatings and the keeping of slaves was legal (and common), it is also important to understand just exactly how advanced the Romans were. The Longman Dictionary of the English Language defines civilised as "of or being peoples of nations in a state of civilisation." And then defines civilisation as "a relatively high level of cultural development; specifically the stage of cultural development at which writing and the keeping of records is attained." I think that by this definition, the Romans were civilised, the educated being able to write and detailed records being kept by many historians. The Romans also had written laws and government, including (later) an assembly for the poorer classes. In fact, their system of law was actually quite advanced (even if it was designed to help the rich) - "The idea was accepted that a man's intentions ought to be taken into account, and there was less importance attached to what he did and what he meant to do. The next thing to become established was the notion that all men must be treated equally." This way of thinking was very advanced and not barbaric or uncivilised at all, in fact the same notion that all men should be treated equally was not established in America, Australia and other countries for many years. It is now common knowledge that, in Ancient Rome, people often attended (and enjoyed) gladiatorial fights to the death, wild beast hunts, naval battles and chariot racing, all which often had religious origins. During the reign of Caesar, thousands of men and animals were butchered just to make a Roman holiday! The Romans also enjoyed pantomimes and plays which too were often very violent in nature - "It was not uncommon for a condemned criminal to be executed [on stage] as part of the play." In modern sources, it is often portrayed that slaves were treated more harshly than was actually the case.

Doud Chronicles Power Trip :: Essays Papers

Doud Chronicles Power Trip The story Disney’s Doug Chronicles Power Trip is about Doug and his problems at school. Doug’s problem was that Vice Principle Bone chose Doug to be the hall monitor. Doug was surprised because he was hand-picked from all the other students. At first Doug thought that it would be dorky, he put on the orange belt but as he was walking to class all the other students were walking the opposite direction, Doug saw he friend, Skeeter. Doug asked â€Å"whats going on?† â€Å"Principle White Announced that there was going to be an assembly in the auditorium,† Skeeter said. The assembly was about a police man from the city, Doug saw how he looked in the uniform and he started day dreaming about him being hall monitor and how he can impress Patti (Doug has a crush on Patti). On Tuesday Doug was doing his regular routine of being the hall monitor, Doug saw Roger the school bully, walking by as the tardy bell rang. Since Doug was new he let him slide and just give him a warning, the other kids in the classroom were amazed that Doug actually stud up to Roger. On Wednesday Doug felt he had more power. A student went up to Doug congratulated him.As Doug was going back to class he saw Roger and his gang in the hall Doug pointed at the clock and Roger left disappointed. On Thursday, Doug was getting a little carried away, he was standing on a stepladder with a megaphone in his hand barking orders. Doug saw Patti running but he just asked â€Å"would you please slow down?† Skeeter walked up to Doug, Skeeter started talking but it seemed that nobody was home. Skeeter walked away mumbling disapoitedly. When Doug went home he still felt like he was in control, he started telling everyone what and what not to do, everyone was angry at Doug. Finally on Friday morning Doug once again caught Patti running, Doug was nervous of what to do, he tried not look at her eyes as he was giving her a detention slip. Patti was undoubtedly upset. Doug really felt bad and he decided to wait for her before she got to detention but unexpectedly it was Vice Principle Bone to arrive first, Doug

How Technological Advancements Have Shaped Social Media Essay

There is no question that technological advancements have shaped the way we carry out our daily lives . There is almost no escaping it. We rely on our cellphones and laptops for nearly everything. Face-to-face social interactions and confrontations are becoming scarce as technology allows teenagers and young adults to hide behind their phones and computers. Young adults, especially high school and college students, need direct social skills to work on group projects in the classroom or to give a good impression in a job interview. I have found oral communication skills to be a vital part of my University degree as it has helped me with various job interviews and presentations. The positive impacts of advancements in technology in terms of social progress are mostly rooted in connection and accessibility. These advancements have allowed the possibility to make new friends or find and connect with long lost friends or relatives. One can easily check in on another and have video chats with the click of an icon whether it be on your laptop or your cell phone using applications such as Facetime. Today many people link their social networking pages and email to their phones so they never miss a beat. The negative effects are due to the fact that people tend to experience less face-to-face interaction in favor of the ability to communicate over the internet or on cell phones (texting). The drawback is that sometimes people use these things as a replacement for in-person relationships. All too often you hear people saying â€Å"Text me† or â€Å"Facebook me†. Internet social interactions also often lead to misunderstandings. With messaging occurring via text or email, connotation and tone are often lost and it is easy for people to misunderstand each other. It is easier for people to become offended this way and can cause problems in relationships. It is evident that technology has really influenced the dynamics of social progress. Only time will tell how it will evolve but I personally believe the pro’s far outweigh the cons. One thing that is for sure is that online social interaction is not going to stop anytime soon.

Literature Review How to write

Literature Review How to write BY Ravit*G1 Article 1 : Writing a Literature Review What is a Literature Review? A literature review is a survey and discussion of the literature in a given area of study. It is a concise overview of what has been studied, argued, and established about a topic, and it is usually organized chronologically or thematically. A literature review is written in essay format. It is not an annotated bibliography, because it groups related works together and discusses trends and developments rather than focusing on one item at a time.It is not a summary; rather, it evaluates previous and urrent research in regard to how relevant and/or useful it is and how it relates to your own research. A Literature Review is more than an Annotated Bibliography or a summary, because you are organizing and presenting your sources in terms of their overall relationship to your own project. Purpose A literature review is written to highlight specific arguments and ideas in a field of study. By highlighting these arguments, the writer attempts to show what has been studied in the field, and also where the weaknesses, gaps, or areas needing further study are.The review should therefore also demonstrate to the reader why the riter's research is useful, necessary, important, and valid. Questions a Literature Review Should Answer: Asking questions such as the following will help you sift through your sources and organize your literature review. Remember, the literature review organizes the previous research in the light of what you are planning to do in your own project. What's been done in this topic area to date? What are the significant discoveries, key concepts, arguments, and/or theories that scholars have put forward? Which are the important works?On which particular areas of the topic has previous research oncentrated? Have there been developments over time? What methodologies have been used? Are there any gaps in the research? Are there areas that haven't been looked at closely yet, but which should be? Are there new ways of looking at the topic? Are there improved methodologies for researching this subject? What future directions should research in this subject take? How will your research build on or depart from current and previous research on the topic? What contribution will your research make to the field?Length The length ofa literature review varies depending on its purpose and audience. In a hesis or dissertation, the review is usually a full chapter (at least 20 pages), but for an assignment it may only be a few pages. Structure There are several ways to organize and structure a literature review. Two common ways are chronologically and thematically. Chronological: In a chronological review, you will group and discuss your sources in order of their appearance (usually publication), highlighting the changes in research in the field and your specific topic over time.This method is useful for papers focusing on research metho dology, historiographical papers, and other writing where time becomes an important lement. For example, a literature review on theories of mental illness might present how the understanding of mental illness has changed through the centuries, by giving a series of examples of key developments and ending with current theories and the direction your research will take. Thematic: In a thematic review, you will group and discuss your sources in terms of the themes or topics they cover.This method is often a stronger one organizationally, and it can help you resist the urge to summarize your sources. By grouping themes or topics of research together, you will e able to demonstrate the types of topics that are important to your research. For example, if the topic of the literature review is changes in popular music, then there might be separate sections on research involving the production of music, research on the dissemination of music, research on the interpretation of music, and hist orical studies of popular music.No matter which method you choose, remember: Within each section of a literature review, it is important to discuss how the research relates to other studies (how is it similar or different, what other studies have been done, etc. as well as to demonstrate how it relates to your own work. This is what the review is for: don't leave this connection out! Source : http://www. smu. ca/ administration/library/litrev. html Article 2 : Write a Literature Review 1.Introduction Not to be confused with a book review, a literature review surveys scholarly articles, books and other sources (e. g. dissertations, conference proceedings) relevant to a particular issue, area of research, or theory, providing a description, summary, and critical evaluation of each work. The purpose is to offer an overview of significant literature published on a topic. 2. Components Similar to primary research, development of the literature review requires four stages: Problem formula tion†which topic or field is being examined and what are its component issues?Literature search†finding materials relevant to the subject being explored Data evaluation†determining which literature makes a significant contribution to the understanding of the topic Analysis and interpretation† discussing the findings and conclusions of pertinent literature Literature reviews should comprise the following elements: An overview of the subject, issue or theory under consideration, along with the bjectives of the literature review Division of works under review into categories (e. g. hose in support of a particular position, those against, and those offering alternative theses entirely) Explanation of how each work is similar to and how it varies from the others Conclusions as to which pieces are best considered in their argument, are most convincing of their opinions, and make the greatest contribution to the understanding and development of their area of researc h In assessing each piece, consideration should be given to: Provenance†What are the author's credentials? Are the author's arguments supported by evidence (e. . primary historical material, case studies, narratives, statistics, recent scientific findings)? Objectivity†ls the author's perspective even- handed or prejudicial? Is contrary data considered or is certain pertinent information ignored to prove the author's point? Persuasiveness†Which of the author's theses are most/least convincing? Value†Are the author's arguments and conclusions convincing? Does the work ultimately contribute in any significant way to an understanding of the subject? 3. Definition and Use/PurposeA literature review may constitute an essential chapter of a thesis or dissertation, or may be a self-contained review of writings on a subject. In either case, its purpose is to: Place each work in the context of its contribution to the understanding of the subject under review Describe the relationship of each work to the others under consideration Identify new ways to interpret, and shed light on any gaps in, previous research Resolve conflicts amongst seemingly contradictory previous studies Identify areas of prior scholarship to prevent duplication of effort Point the way forward for further researchPlace one's original work (in the case ot theses or dissertations) in the context ot existing literature The literature review itself, however, does not present new primary scholarship. http://library. ucsc. edu/help/howto/write-a-literature-review What is a review of the literature? A literature review is an account of what has been published on a topic by accredited scholars and researchers. Occasionally you will be asked to write one as a separate assignment (sometimes in the form of an annotated bibliography†see the bottom of the next page), but more often it is part of the introduction to an essay, research eport, or thesis.In writing the literature revie w, your purpose is to convey to your reader what knowledge and ideas have been established on a topic, and what their strengths and weaknesses are. As a piece of writing, the literature review must be defined by a guiding concept (e. g. , your research objective, the problem or issue you are discussing, or your argumentative thesis). It is not Just a descriptive list of the material available, or a set of summaries Besides enlarging your knowledge about the topic, writing a literature review lets you gain and demonstrate skills in two areas 1 . formation seeking: the ability to scan the literature efficiently, using manual or computerized methods, to identify a set of useful articles and books 2. critical appraisal: the ability to apply principles of analysis to identify unbiased and valid studies. A literature review must do these things 1 . be organized around and related directly to the thesis or research question you are developing 2. synthesize results into a summary of what is and is not known 3. identify areas of controversy in the literature 4. ormulate questions that need further research Ask yourself questions like these: . What is the specific thesis, problem, or research question that my literature review helps to define? 2. What type of literature review am I conducting? Am I looking at issues of theory? methodology? policy? quantitative research (e. g. on the effectiveness of a new procedure)? qualitative research (e. g. , studies )? 3. What is the scope of my literature revie w? What types ot publications am I using (e. g. , Journals, books government documents, popular media)?What discipline am I working in (e. g. , nursing psychology, sociology, medicine)? 4. How good was my information seeking? Has my search been wide enough to ensure I've found all the relevant material? Has it been narrow enough to exclude irrelevant material? Is the number of sources I've used appropriate for the length of my paper? 5. Have I critically analysed the litera ture I use? Do I follow through a set of concepts and questions, comparing items to each other in the ways they deal with them?

Puberty Blues Essay

The TV show I have chosen to talk to you about today is Puberty Blues. It is aired at 8:30pm, Wednesday on channel 10. It doesn’t have a specific genre, but more like a mixture. I would classify it as a teen drama. Puberty Blues doesnt work in plot twists but offers a suprising reality. The best part about the TV drama for me is how we get a glimpse into the life of a 1970’s teenager. Puberty Blues is set in Cronulla, Sydney, in the late 1970’s. Majority of the time, Debbie and Sue’s houses are used, but the ‘greenhill gang’ are also featured hanging around by the beach. Puberty Blues tells the story Debbie Vickers and Sue Knights. They are both very clever but somewhat unpopular high school girls who wants to raise their social standings in order to go out with boys. Through out the episodes we get to know the girls’ parents- Judy and Martin who are closed off and don’t interact with each other much and Pam and Roger who have a far more open relationship. The sixth episode was directed by Glendyn Ivin and written by Fiona Seresis. The main plot is when the ‘greenhill gang’ including Debbie and Sue, get wasted, go driving and flip the car, killing the driver. Any other show would have sent the characters into an instant panic but the writers of Puberty Blues understand that the shock combined with drugs would have caused everyone to burst into disbelieving laughter. The car crash wasn’t the only plot in the episode though. Debbies parents, Judy and Martin, got to couples councilling because Martin has strong feelings for a women at his work. Cheryl, a member of the ‘green hills’ gang, is flirting with her mum’s boyfriend to prove she is more desirable than her mother, who resents. The social issue pressented in the show was definitely driving under the influence. This message is easily interpreted in the car crash scene were the driver and passengers are drunk and stoned. This wasn’t my favourite episode from Puberty Blues but it was still solid like we have come to expect from this series. I would recommend the show to high school students and older as there are some mature themes and sexual references. I love this show because it takes awkward and serious situations and brings out their bright side.

Ibdp Biology Sl Specimen Exam Paper

N08/4/BIOLO/SPM/ENG/TZ0/XX+ 88086004 Biology Standard level PaPer 1 Monday 17 November 2008 (afternoon) 45 minutes INSTRUCTIONS TO CANDIDATES †¢ †¢ †¢ Do not open this examination paper until instructed to do so. Answer all the questions. For each question, choose the answer you consider to be the best and indicate your choice on the answer sheet provided. 8808-6004 13 pages  © International Baccalaureate Organization 2008 –– 1. Which of the following characterizes tissues? A. B. C. D. A group of cells that develop independently. A group of organs that have the same function. A group of cells that have the same function.A group of organs that have the same structure. N08/4/BIOLO/SPM/ENG/TZ0/XX+ 2. Which of the following explains how brain cells develop to carry out their functions? A. B. C. D. The cells have interacted to become brain cells. The cells have evolved that way. Some genes are expressed while other genes are not. All genes are expressed in the brain cells. 3. The following is a diagram of a prokaryote. I. II. III. IV. Which two structures are required for protein synthesis in this cell? A. B. C. D. 8808-6004 III and IV II and IV II and III I and II } –– 4. What is necessary for osmosis to occur? A. B. C. D.A membrane protein A partially permeable membrane A source of energy A cell wall N08/4/BIOLO/SPM/ENG/TZ0/XX+ 5. In a cell the nuclear membrane has broken down and spindle microtubules from both poles are attached to each centromere of chromosomes aligned on the equator. Which phase of mitosis does this describe? A. B. C. D. Prophase Anaphase Metaphase Telophase 6. Which of the following contain the element phosphorus? A. B. C. D. Amino acids Viruses Ribose Deoxyribose 8808-6004 Turn over –4– 7. Which diagram correctly illustrates a glucose molecule? A. H C OH CHOH C H OH C H C. H N H C H N08/4/BIOLO/SPM/ENG/TZ0/XX+B. O H C OH O C H N H C H C OH CHOH C H H C OH O H H C OH C OH H C OH H O D. CH (CH)n C O OH 8. The following diagram shows the effect of temperature on enzyme activity. What explains the lack of activity at high temperatures? Rate of enzyme activity optimum temperature Temperature /  °C A. B. C. D. The active site no longer has the required shape. All the substrate has been used. All the enzyme has been used. Theactivesiteiscompletelyfilledwithsubstrate. 8808-6004 –– 9. N08/4/BIOLO/SPM/ENG/TZ0/XX+ Which of the following correctly show the process and location for pyruvate formation? Process A. B. C. D. erobic cell respiration respiration photosynthesis photosynthesis Location cytoplasm chloroplast cytoplasm chloroplast 10. A molecule has two guanines, one cytosine, three riboses and three phosphates arranged in a single strand. What kind of molecule is this? A. B. C. D. DNA RNA A triplet of DNA nucleotides A polysaccharide 11. In photosynthesis, light energy is used to split water molecules. Which products are formed and what is the name of the reaction? Products formed A. B. C. D. hydrogen and ATP hydrogen and oxygen hydrogen and ATP hydrogen and oxygen Reaction photolysis photolysis hydrolysis hydrolysis 8808-6004 Turn over 6– 12. What can be concluded from the following data? N08/4/BIOLO/SPM/ENG/TZ0/XX+ 1   4  6 7 8  10 11 1 1 14 1 16 17 18 1 0 1  X Y A. B. C. D. Karyotype of a male with a normal set of chromosomes DNAprofilingofamalewithDownsyndrome DNAprofilingofamalewithanormalsetofchromosomes Karyotype of a male with Down syndrome 13. The genotypes of two parents are HbA HbA and HbA HbS. What are the likely phenotypes of their children? A. B. C. D. 7 % healthy 0 % may develop sickle-cell anemia  % may develop sickle-cell anemia 100 % healthy 8808-6004 –7– 14. N08/4/BIOLO/SPM/ENG/TZ0/XX+ The gel image shown below has two lanes.The DNA is loaded onto the gel at the origin. To separate the DNA fragments a negative charge is applied to the origin of the gel. What conclusi on could be made about the DNA fragments? 1 origin  A. B. C. D. The size of the DNA fragment in Lane 1 is greater than in Lane . The charge of the DNA fragment in Lane  is positive. The size of the DNA fragment in Lane  is greater than in Lane 1. The charge of the DNA fragment in Lane 1 is positive. 15. Which of the following best describes sex linkage? A. B. C. D. The condition will be inherited only by sons. The condition will be inherited only by daughters.The condition may be inherited by sons and daughters. The condition will be inherited by more daughters than sons. 16. A human gene is cloned into a plasmid and put into a host cell. Which enzymes are used for this gene transfer? A. B. C. D. Restriction endonuclease and DNA ligase DNA polymerase and DNA ligase Restriction endonuclease and DNA polymerase DNA polymerase and RNA polymerase 8808-6004 Turn over –8– 17. N08/4/BIOLO/SPM/ENG/TZ0/XX+ Which of the following best describe(s) all the descendants of a clon e? I. II. III. A. B. C. D. I only I and II only I and III only I, II and III They have the same chromosomes.They share one parent. They are sterile. The following diagram of a food web refers to questions 18 and 19. hawk fox small birds badger hedgehog shrew beetles slugs mice woodlice rabbits grass 18. Which organism(s) in the food web above is(are) both secondary consumer(s) and tertiary consumer(s)? A. B. C. D. Hawk and fox Hawk and hedgehog Fox and badger Hawk only 8808-6004 –– 19. N08/4/BIOLO/SPM/ENG/TZ0/XX+ If 1 000 000 J m– yr–1 of sunlight is assimilated by the grass in the food web, how much energy would be available to the badger? A. B. C. D. 10 to  J m– yr–1 100 to 00 J m– yr–1 00 to 1000 J m– yr–1 00 to 10 000 J m– yr–1 0. The average weight of walnuts from one group of trees was 8.  g with a standard deviation of 1.  g. Which conclusion can be drawn from these data? A. B. C . D.  % of all walnuts from these trees weigh between .  g and 11.  g. 68 % of all walnuts from these trees weigh between .  g and 11.  g. The minimum weight of walnuts from this tree is .  g. The maximum weight of walnuts from this tree is 11.  g. 21. Which of the following gases contribute to the greenhouse effect? I. II. III. A. B. C. D. I only I and II only II and III only I, II and III Methane Water vapour Nitrogen 8808-6004 Turn over – 10 – 22.What is the main cause of variation in a species? A. B. C. D. Meiosis Mitosis Random mating Emigration N08/4/BIOLO/SPM/ENG/TZ0/XX+ 23. The diagram below represents the human digestive system. 1 4   Which of the following correctly represents the labels? Esophagus A. B. C. D. 1 1 4  Gall bladder 4 4  1 Small intestine   1  Pancreas    4 8808-6004 – 11 – 24. What type of blood does the left atrium of the heart receive? A. B. C. D. Deoxygenated blood from the lungs Oxygenated blood from the r ight ventricle Oxygenated blood from the lungs Deoxygenated blood from the left ventricle N08/4/BIOLO/SPM/ENG/TZ0/XX+ 5. What will be an effect of HIV infection on the immune system? A. B. C. D. Antigens no longer bind to antibodies. Number of active lymphocytes is increased. Antibody production is limited. HIV patient will fall ill more frequently. 26. A person is suffering from an illness and the doctor prescribes an antibiotic to treat the disease. What is the patient likely to suffer from? A. B. C. A viral infection A prokaryotic infection An eukaryotic infection Theflu(influenza) D. 8808-6004 Turn over – 1 – 27. N08/4/BIOLO/SPM/ENG/TZ0/XX+ The diagram below shows the female reproductive system and associated organs.X Y Z Which of the labelled structures correctly identify the cervix, urethra and ovary? Cervix A. B. C. D. Z Y Y Z Urethra X Z X Y Ovary Y X Z X 28. Which conditions apply to gas exchange in the lungs when the blood arrives there from the body? Blood oxygen concentration A. B. C. D. same as inhaled air higher than inhaled air lower than inhaled air same as inhaled air Blood carbon dioxide concentration higher than inhaled air lower than inhaled air higher than inhaled air lower than inhaled air 8808-6004 – 1 – 29. Which of the following events leading up to birth is correct?A. B. C. D. Progesterone levels increase, oxytocin decreases. Progesterone levels decrease, oxytocin increases. Progesterone levels increase, oxytocin increases. Progesterone levels decrease, oxytocin decreases. N08/4/BIOLO/SPM/ENG/TZ0/XX+ 30. What should happen after a meal? A. B. C. D. Blood glucose concentration rises and insulin concentration increases. Blood glucose concentration decreases and glucagon increases. Blood glucose concentration rises and insulin concentration decreases. Blood glucose concentration rises and glucagon concentration stays the same. 8808-6004

Achievement standard 91329 study exemplar Essay Example for Free (#91329)

Achievement standard 91329 study exemplar Essay ? Anaerobic training is used to enhance performance in non-endurance activities to promote strength, speed and power and also to strengthen muscles in a shorter amount of time. Anaerobic training triggers two main energy systems: the high energy phosphate systems, (adenine triphosphate (ATP) and creatine phosphate (CP)) and the anaerobic glycolysis system. High energy phosphates are used in small doses within muscle cells and the anaerobic glycolysis system is used in the absence of oxygen inside the cells or when ATP is needed in higher quantities but it cannot be produced fast enough during aerobic metabolism. These energy systems will help to build strength within the muscles and will contribute to a better health and well-being. Demonstrate in-depth understanding on the bodies’ physiological responses from participating in the session. During my training my body was exerting a lot of ATP around my body to give me energy to do the workout. I worked between 75-90% of my max heart rate because the workouts I was doing were very short but intense which meant I had to work harder to get the maximum amount of ATP out of my body. I noticed that after my workouts I was fatigued because the ATP energy within the muscle cells around the area of work had been all used up. Demonstrate comprehensive understanding of the strength and weaknesses of the application of the method of training. You should show an interrelationship between the biophysical principles. Anaerobic training is really good in context to the various sports I participate in because in netball, basketball and touch you are not always on the move but you have to exert small bursts of energy at a time e.g. following the opposition on defence, dribbling the ball towards the hoop and running with the touch ball. The small exerts of energy are using a high build-up of ATP within the muscle cells. Being able to keep working through the pain of working at a 75-90% max heart rate helps to burn fat faster and build muscle. Task 3: Demonstrate comprehensive understanding of the application of biophysical principles. (a)Demonstrate comprehensive understanding of the application of three methods of training (methods of training may include: continuous, fartlek, circuit, interval (short and long), flexibility, resistance and plyometric) you have used in your training programme. Method of training: Short interval training I used short interval training in my training programme because I wanted to challenge myself and improve my health and well-being in a short amount of time. I order to do this I had to work between a 75-90% max heart rate so that my muscles and heart were working as hard as they could to produce maximum physical results. I decided to work at a 2:1 work/rest ratio so my body had enough rest to produce more ATP and so my heart rate can lower a bit so I have to work harder to build it up again. I tried to move as little as possible during rest time so my body has enough time to lower as low as it possibly can before rising again to the same heart rate. During my training I noticed that I was talking to myself various times in a workout telling myself to keep going and reminding myself of the number of reps that were left. This showed that my brain was also being trained along with my muscles and the brain is one of the hardest muscles to train in the body. Method of training: Plyometric training I used plyometric training to build power and speed in my legs by speed skipping and double under skipping. This type of training is important to building power and speed in my lower body by pushing my muscles to move from extension to contraction in a short time at an explosive rate. When doing double under skipping I experienced very small shocks on landing in which my hip, knee and ankle extensors endured a powerful eccentric contraction. When this happened my muscles were forced to tense. The eccentric contraction is then quickly switched to the isometric (when I stopped moving downwards) and then the concentric contractions, in a rapid time frame which is repeated many times. Isometric contraction always occurs in the transition from the  eccentric to the concentric contraction, but in this rapid transition it is practically eliminated. This is builds strength in legs which can be important to runners when leaving a starting block. The reason why I used this method of training was mainly to build strength in my legs which is beneficial to my lower body. Method of training: Fartlek training Fartlek training was used in my training programme to provide variation to the normal training I did. This placed stress on my aerobic and anaerobic systems and I allowed me to work as fast or as slow as I needed to. Between the high intensity running, I did easy and less strenuous jogging to recover for the next high intensity sprint and I could alter the periods of time that I did high intensity and low intensity running which was a bonus to myself. The benefits of the fartlek training were that I could alter the intensity level to suit myself and it was effective to have the two intensities put into one workout. Having this choice to alter the workout did not stop me from pushing myself though. Fartlek training helped to strengthen my legs and improve my breathing so I could maintain at a high speed for a longer period of time. Choose four principles of training. Principles of training may include the F.I.T.T principle (frequency, intensity, time, type), as well as specificity, progression, reversibility, rest and variety. Demonstrate in depth how and why these were applied to the methods of training in your programme. Principle of training: Intensity How did you apply it to your training programme? I specified the intensity of the workout on my training programme before I started working out so I knew to work at a high intensity or a low intensity. To work out my max heart rate I used the max heart rate chart on the wall in the weights room and I double checked it by using the max heart rate formula: 220 – age, which made my max heart rate 204 bpm. I specified in my training programme that I would be working between 75% and 90% of my max heart rate so I used a heart rate app on my phone because we did not have a heart rate monitor at school and double checked it by putting my hand on my pulse and timing it with a stop watch for a minute which would give me  my bpm straight after the workout. This would ensure that I was working between 150-180 bpm. Why did you apply it to your training programme? I applied intensity in my training programme because it kept my heart rate between the 75% and 90% max heart rate. I was working at a very high intensity which caused oxygen transfer into my muscles to be harder. Due to the anaerobic training I did in my training programme, the periods of time I could work within the 75-90% max heart rate area increased and I could easily get rid of the lactic acid that had built up to use within other energy systems in my body. Principle of training: Frequency How did you apply it to your training programme? I ensured that before I started my training programme that I would be training on specific days within the three week period that we were given to complete the training. I wrote these dates down before I started, determining which days I would train and which days I would rest. This assured the teacher supervising and I that I had to follow this plan and stick to the days designated for training. Why did you apply it to your training programme? I applied frequency in my training programme because it helped to balance the amount of stress I put on myself to adapt to the training and allowing enough time to rest and recover. In addition with the foods I ate within the time allocated to train, training frequently (about 4 or 5 times a week) helped my body to burn calories for my health and well-being in which my training programme was intended to improve. Principle of training: Specificity  How did you apply it to your training programme?  To apply specificity in my training programme I had to do a lot of written work before I had even started training. Not only did I specify the days on which I would train or rest, I had to also specify the amount of time I was going to train or do each activity for, what type of training was going to be involved on each day, what specific activities I was going to do with or without equipment on each day and the max heart rate area I was going to be  working within for the day’s session. I did this by writing all down in my training programme before the three week period and then following each session recorded for each date. Because I was merely training to improve my health and well-being I could do a variety of training within my training programme to improve specific parts of my body e.g. plyometric training to build speed and strength in my lower body and fartlek training to improve my breathing while running. Why did you apply it to your training programme? I applied specificity in my training programme because it was forward thinking and helped me to stick to the plan I had set out and be more organised on the training day. Because my training programme was designed specifically to improve my health and well-being I was not training for a purpose such as interval sprints to improve 100m sprints. Making sure that each training session was specific allowed me to train various parts of my body rather than training for a specific activity likt long distance running. Principle of training: Variety How did you apply it to your training programme? I used different methods of training within my training programme to create variety. Each training session in my training programme was different and I was using a different method of training each day e.g. On Monday 26th August 2013, I used plyometric training as my method of training followed by short interval training on Tuesday 27th August 2013. I also mixed methods of training in my workout to create even more variety and test my body’s adaption capacity e.g. adding skipping in to a short interval workout to incorporate a plyometric aspect into my workout. Why did you apply it to your training programme? The main reason I applied variety in my training programme was to prevent boredom from doing the same thing during the three week training period. In my training programme not one training session was the same, some consisted of elements from other sessions but none were exactly the same. I did this because it gave me a chance to work different areas of my body using different methods of training. Training programme evaluation Strengths of training programme. I think that the main strength in my training programme was the variety and intensity that my training programme offered. Due to the lack of specified purpose for training, I could experiment with my trainings and evaluate on whether that session was a success or needed improvement. This proved to be a benefit for my body because I was able to work all parts of my body in the one workout rather that working on only one area of my body. This provided minute amounts of muscle and resistance of energy system developments which was a huge benefit to my psychological health because I knew that this training was working and gave me more self-confidence. Because I added variety into my training programme, especially into my short interval training, it helped to build strength and speed faster than if I did the same training each session. Another strength within my training programme was the simplicity of it. It was easy to follow and I didn’t need to use much equipment in the gym which makes my training programme easy to follow and someone else could easily use it to train with. Weaknesses of training programme. Using methods of training that worked mainly my lower body was one of my weaknesses because it did not provide me with adequate upper body training. Because I used plyometric and fartlek training methods which both worked my lower body muscle groups and they did not benefit my upper body. Also the duration of the short interval training session I did were a bit too long, especially during the first week of the training period, so I was fatigued very early in the session and it was hard to carry on working at the rate I started at. What modifications would you make to the application of the biophysical principles used in your programme? To improve the application of my biophysical principles used in my programme, I would alter it to focus on one specific physical activity but only doing different kinds of workouts that will help to improve that physical activity like doing different workouts focusing on running if I wanted to improve my running skills. Doing this will allow me to accurately measure whether my training is working by looking at results from before I started training and after I have finished training. I would also start with low intensity workouts during the first  week and then eventually elevating the intensity over the weeks following to minimise the fatigue levels while working out. By doing this it will allow my body time to adapt to the intensity and stress of the workouts. Achievement standard 91329 study exemplar. (2016, May 12).